The biolutoxR package is useful for data analysis of toxicity tests based on bacterial bioluminescence inhibition.
A detailed presentation of this tool is available in the following article: in prep.
Bacterial bioassays using bioluminescence inhibition are used to assess the bioluminescent response of bacteria to exposure to a solution of interest at different exposure times, typically 5, 15 and 30 minutes. Under optimal conditions, these bacteria produce bioluminescence. This bioluminescence is directly linked to the respiratory metabolic process of the bacteria. However, when bacteria are exposed to a toxic substance, this metabolic process is disrupted, leading to an inhibition of bioluminescence. This reaction is therefore exploited in this type of test to study the direct link between light intensity and the level of toxicity of a sample of interest compared with a control sample.
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Text and figures are licensed under Creative Commons Attribution CC BY-SA 4.0. Source code is available at https://github.com/bbellier/biolutoxR_website.com, unless otherwise noted. The figures that have been reused from other sources don't fall under this license and can be recognized by a note in their caption: "Figure from ...".